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Controlling Focal Adhesion Kinase (FAK) Protein Kills Cancer Cells Study Shows

By | September 26th, 2015 | Modified - September 26th, 2015
Controlling Focal Adhesion Kinase (FAK) Protein Kills Cancer Cells Study Shows
Controlling Focal Adhesion Kinase (FAK) Protein Kills Cancer Cells Study Shows

A study[1][2] published in the Cell journal on September 24, 2015 showed a new drug holds promise for curing cancer. The researchers in the study indicated that cancer cells use the Focal Adhesion Kinase (FAK) protein to avoid attacks by the immune system.

The body normally uses the FAK protein to support healthy cell growth and transportation. Cancer cells are able to manipulate the FAK protein’s normal role in supporting healthy cell proliferation, and use the protein to change immune system’s response to help the survival of cancer cells instead of killing them.

The researchers found that the cancer cells’ manipulation of the FAK protein promoted tumor evasion by inducing an “immuno-suppressive microenvironment.” The FAK protein was used to transcribe chemokines that recruit Tregs, which inhibit cytotoxic CD8+ T cells and allowed for tumor tolerance and growth.

An experimental FAK inhibitor was used in the study that prevented the manipulation of the immune response and allowed the immune system to see the cancer cells as a threat and kill them.

Dr. Alan Serrels, researcher in the study, said:

FAK is hi-jacked by cancer cells to protect them from the immune system. This exciting research reveals that by blocking FAK, we’ve now found a promising new way to help the immune system recognise the cancer and fight it.[3]

The research was done with mice with squamous cell carcinoma skin cancer and all of the tumors were killed using the FAK inhibitor. The treatment is also likely to be successful against other types of cancer.

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Alklaine Plant Based Diet
Alklaine Plant Based Diet

About Author:

Aqiyl Aniys is the author of the book Alkaline Herbal Medicine, the Alkaline Plant Based Diet book, and the children's book, Faith and Justice eat an Alkaline Plant Based Diet." He received a certificate in plant-based nutrition from Cornell University, a BA in Organizational Behavior and Communications from NYU, worked as an elementary school teacher, and studied social work. He enjoys boxing, kick boxing, cycling, power walking, and basically anything challenging, and his alkaline plant-based diet supports all that he does. Learn more about transitioning to avegan diet using the Dr. Sebi nutritional guide.

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